Transition to psychosis was measured with the Comprehensive Assessment of At-Risk Mental States, Brief Psychiatric Rating Scale/Comprehensive Assessment of Symptoms and History, or state public mental health records. During the time to follow-up, 114 of the 416 participants were known to have developed a psychotic disorder. The highest risk for transition was within the first two years of entry into the service, but individuals continued to be at risk up to 10 years after initial referral. The overall rate of transition was estimated to be 34.9 percent over a 10-year period.
“Long duration of symptoms, low functioning, negative symptoms, and disorders of thought content predicted psychosis," the researchers said. "Ongoing research is needed to identify additional robust predictors. Services should aim to follow up patients for at least two years. Individuals with a long duration of symptoms and poor functioning may need closer monitoring.”
The study is posted here. For more information on psychosis risk, see Psychiatric News here.
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