Investigators will have to identify a target or mediator on which the intervention must have some effect, as well as influencing symptoms, said Insel. Researchers will also have to move more quickly through the approval, recruitment, and completion processes. They must meet stringent transparency standards for trial registration, monitoring human protection, and posting their results. Finally, new clinical trials will not be supported under previous funding announcements.
“We believe that better outcomes will require a deeper understanding of the disorders,” he said. “These new clinical trials are designed to provide that.”
To read more in Psychiatric News about clinical trials in psychiatry, see the article, “Psychiatrist Norquist Chairs Outcomes-Research Project.”