---
title: "Psych News Alert: Smoking Linked to Depression, Risk for Suicide"
description: Grandpa/Shutterstock Researchers at the Washington University School of Medicine’s Department of Psychiatry recently carried out genetic l...
image: https://alert.psychnews.org/hubfs/Imported_Blog_Media/smoking%20depressed%20man_32010580-Jun-24-2025-03-52-53-6069-PM.jpg
---

 6/24/24 11:16 AM

# Smoking Linked to Depression, Risk for Suicide

![Picture of Psychiatric News Alert](https://alert.psychnews.org/hs-fs/hubfs/Psych%20News%20Email%20Banners/PN-Blue-Box_rgb.png?width=50&name=PN-Blue-Box_rgb.png) [ Psychiatric News Alert ](https://alert.psychnews.org/author/psychiatric-news-alert)

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Researchers at the Washington University School of Medicine’s Department of Psychiatry recently carried out genetic linkage analyses of DSM-IV-diagnosed major depressive disorder in two samples that are part of the Nicotine Addiction Genetics project, an international consortium focused on tobacco dependence. “We used an affected sibling-pair design, in which at least two adult offspring per family reported a history of DSM-IV major depressive disorder, and tested for linkage,” said the group in its report. “Results appear to confirm a genome-wide significant linkage signal at chromosome 3p25-3p26.” The authors note that their finding, in light of previous studies, raises the possibility of common genetic influences across major depressive disorder and smoking-related behavior, or of gene-by-environment (i.e., smoking) interaction effects on major depressive disorder.

Nicotine dependence has been identified as a risk factor for suicide attempts. Read more about it at [http://pn.psychiatryonline.org/content/46/3/16.2.full](http://pn.psychiatryonline.org/content/46/3/16.2.full) .

[suicide](https://alert.psychnews.org/tag/suicide), [smoking](https://alert.psychnews.org/tag/smoking), [depression](https://alert.psychnews.org/tag/depression)

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