---
title: "Psych News Alert: Alzheimer’s Association Research Roundtable Workgroup Releases Report"
description: Kheng Guan Toh/Shutterstock The Alzheimer’s Association Research Roundtable Workgroup has published its findings and conclusions in the curr...
image: https://alert.psychnews.org/hubfs/Imported_Blog_Media/alzheimer%20word%20cloud_29306674-4.jpg
---

 7/15/11 12:00 AM

# Alzheimer’s Association Research Roundtable Workgroup Releases Report

![Picture of Psychiatric News Alert](https://alert.psychnews.org/hs-fs/hubfs/Psych%20News%20Email%20Banners/PN-Blue-Box_rgb.png?width=50&name=PN-Blue-Box_rgb.png) [ Psychiatric News Alert ](https://alert.psychnews.org/author/psychiatric-news-alert)

Share: [facebook-f icon ](http://www.facebook.com/share.php?u=https://alert.psychnews.org/2011/07/alzheimers-association-research.html) [linkedin-in icon ](http://www.linkedin.com/shareArticle?mini=true&url=https://alert.psychnews.org/2011/07/alzheimers-association-research.html) [Twitter icon ](https://twitter.com/intent/tweet?url=https://alert.psychnews.org/2011/07/alzheimers-association-research.html) [pinterest-p icon ](http://pinterest.com/pin/create/link/?url=https://alert.psychnews.org/2011/07/alzheimers-association-research.html) [envelope icon ](mailto:?body=https://alert.psychnews.org/2011/07/alzheimers-association-research.html)

| <https://blogger.googleusercontent.com/img/b/R29vZ2xl/AVvXsEiSiBzsepTLxoWgWjHntaiWmYO9ZL77aBeqcUizDwPXCvpaidkVXlBkQSQoIp3o0z2cqpGgqv4jXW_E4o_wPiYJj1uNHW06UK87M1A0w9LVu4K3TC4xYXgwAB2SrxNqfwGlJehE62HOGRn2/s1600/alzheimer+word+cloud_29306674.jpg> |
| --- |
| Kheng Guan Toh/Shutterstock |

The Alzheimer’s Association Research Roundtable Workgroup has published its findings and conclusions in the current issue of *Alzheimer’s & Dementia*, including recommendations for conducting clinical trials of amyloid-lowering agents. The  group was convened in July 2010 to review publicly available trial data in response to advice from the Food and Drug Administration (FDA) to sponsors conducting clinical trials with amyloid-lowering agents for  treating Alzheimer’s. The FDA raised concerns about potential adverse events, specifically cerebral microhemorrhage and vasogenic edema, and recommended discontinuation in patients with any microhemorrhages during the study, advice that appeared stringent and limiting to many researchers.

Prior to publication, the workgroup report was sent to the FDA for review, and the FDA subsequently revised and updated its original advice to sponsors in a manner consistent with the report.

Amyloid-lowering agents are one approach to amyloid in the brain currently being investigated. To read about another approach, see *Psychiatric News* at [http://pn.psychiatryonline.org/content/46/9/18.1.full.](http://pn.psychiatryonline.org/content/46/9/18.1.full.)

[Alzheimer’s](https://alert.psychnews.org/tag/alzheimers), [Alzheimer's Association](https://alert.psychnews.org/tag/alzheimers-association), [beta-amyloid](https://alert.psychnews.org/tag/beta-amyloid), [amyloid-lowering agent](https://alert.psychnews.org/tag/amyloid-lowering-agent)

## Related posts

[![](https://alert.psychnews.org/hs-fs/hubfs/Imported_Blog_Media/FDA_NewLogo_1-Jun-24-2025-04-35-16-7822-PM.jpg?height=200&name=FDA_NewLogo_1-Jun-24-2025-04-35-16-7822-PM.jpg) ](https://alert.psychnews.org/2023/01/fda-approves-second-monoclonal-antibody.html)

[Alzheimer's disease](https://alert.psychnews.org/tag/alzheimers-disease), [FDA](https://alert.psychnews.org/tag/fda), [drug development](https://alert.psychnews.org/tag/drug-development), [New England Journal of Medicine](https://alert.psychnews.org/tag/new-england-journal-of-medicine), [amyloid plaques](https://alert.psychnews.org/tag/amyloid-plaques), [monoclonal antibody](https://alert.psychnews.org/tag/monoclonal-antibody), [Leqembi](https://alert.psychnews.org/tag/leqembi), [lacanemab](https://alert.psychnews.org/tag/lacanemab)

## [FDA Approves Second Monoclonal Antibody Medication for Alzheimer’s](https://alert.psychnews.org/2023/01/fda-approves-second-monoclonal-antibody.html)

![Picture of Psychiatric News Alert](https://alert.psychnews.org/hs-fs/hubfs/Psych%20News%20Email%20Banners/PN-Blue-Box_rgb.png?width=50&name=PN-Blue-Box_rgb.png) [Psychiatric News Alert](https://alert.psychnews.org/author/psychiatric-news-alert) 

 1/9/23 12:00 AM

[ Read more ](https://alert.psychnews.org/2023/01/fda-approves-second-monoclonal-antibody.html)

[![](https://alert.psychnews.org/hs-fs/hubfs/Imported_Blog_Media/beta%20amyloid%20chemical%20structure_102810080-Jun-24-2025-06-23-59-4554-PM.jpg?height=200&name=beta%20amyloid%20chemical%20structure_102810080-Jun-24-2025-06-23-59-4554-PM.jpg) ](https://alert.psychnews.org/2012/07/hopes-fade-for-alzheimer-treatment.html)

[Alzheimer's disease](https://alert.psychnews.org/tag/alzheimers-disease), [beta-amyloid](https://alert.psychnews.org/tag/beta-amyloid), [bapineuzumab](https://alert.psychnews.org/tag/bapineuzumab)

## [Hopes Fade for Alzheimer's Treatment Breakthrough](https://alert.psychnews.org/2012/07/hopes-fade-for-alzheimer-treatment.html)

![Picture of Psychiatric News Alert](https://alert.psychnews.org/hs-fs/hubfs/Psych%20News%20Email%20Banners/PN-Blue-Box_rgb.png?width=50&name=PN-Blue-Box_rgb.png) [Psychiatric News Alert](https://alert.psychnews.org/author/psychiatric-news-alert) 

 7/24/12 12:00 AM

Results from a phase 3 clinical trial of a once-promising new medication to treat Alzheimer's...

[ Read more ](https://alert.psychnews.org/2012/07/hopes-fade-for-alzheimer-treatment.html)

[![](https://alert.psychnews.org/hs-fs/hubfs/Imported_Blog_Media/older_couple_iStock-1029343092-Jun-24-2025-10-31-54-7102-PM.jpg?height=200&name=older_couple_iStock-1029343092-Jun-24-2025-10-31-54-7102-PM.jpg) ](https://alert.psychnews.org/2019/12/subtle-cognitive-deficits-may-precede.html)

[Alzheimer's disease](https://alert.psychnews.org/tag/alzheimers-disease), [language](https://alert.psychnews.org/tag/language), [mild cognitive impairment](https://alert.psychnews.org/tag/mild-cognitive-impairment), [Adam M. Brickman](https://alert.psychnews.org/tag/adam-m-brickman), [entorhinal cortex](https://alert.psychnews.org/tag/entorhinal-cortex), [attention](https://alert.psychnews.org/tag/attention), [amyloid](https://alert.psychnews.org/tag/amyloid), [Beth E. Snitz](https://alert.psychnews.org/tag/beth-e-snitz), [memory](https://alert.psychnews.org/tag/memory), [Neurology](https://alert.psychnews.org/tag/neurology), [Kelsy Thomas](https://alert.psychnews.org/tag/kelsy-thomas)

## [Subtle Cognitive Deficits May Precede Amyloid Accumulation in Alzheimer’s, Study Suggests](https://alert.psychnews.org/2019/12/subtle-cognitive-deficits-may-precede.html)

![Picture of Psychiatric News Alert](https://alert.psychnews.org/hs-fs/hubfs/Psych%20News%20Email%20Banners/PN-Blue-Box_rgb.png?width=50&name=PN-Blue-Box_rgb.png) [Psychiatric News Alert](https://alert.psychnews.org/author/psychiatric-news-alert) 

 12/31/19 12:00 AM

In the progression of Alzheimer’s disease (AD), subtle cognitive difficulties may develop prior to...

[ Read more ](https://alert.psychnews.org/2019/12/subtle-cognitive-deficits-may-precede.html)

```json
{
  "@context" : "https://schema.org",
  "@type" : "BlogPosting",
  "author" : {
    "@type" : "Person",
    "name" : "Psychiatric News Alert",
    "url" : "https://alert.psychnews.org/author/psychiatric-news-alert"
  },
  "dateModified" : "2025-06-24T22:50:10.796Z",
  "datePublished" : "2011-07-15T04:00:00.000Z",
  "headline" : "Psych News Alert: Alzheimer’s Association Research Roundtable Workgroup Releases Report",
  "image" : [ "https://alert.psychnews.org/hubfs/Imported_Blog_Media/alzheimer%20word%20cloud_29306674-4.jpg" ],
  "mainEntityOfPage" : {
    "@id" : "https://alert.psychnews.org/2011/07/alzheimers-association-research.html",
    "@type" : "WebPage"
  },
  "publisher" : {
    "@type" : "Organization",
    "logo" : {
      "@type" : "ImageObject",
      "url" : "https://alert.psychnews.org/hubfs/PN-Blue-Box.jpg"
    }
  }
}
```