---
title: "Psych News Alert: Study Finds Gabapentin May Be Effective in Treating Alcohol Dependence"
description: Researchers at the Scripps Research Institute report data suggesting that the anticonvulsant drug gabapentin may be effective in the treatme...
image: https://alert.psychnews.org/hubfs/Imported_Blog_Media/alcohol%2c%202%20glasses%20of_79511350-Jun-24-2025-04-13-11-5798-PM.jpg
---

 11/21/13 12:00 AM

# Study Finds Gabapentin May Be Effective in Treating Alcohol Dependence

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Researchers at the Scripps Research Institute report data suggesting that the anticonvulsant drug gabapentin may be effective in the treatment of some patients with alcohol dependence and the relapse-related symptoms of insomnia, dysphoria, and craving, with a favorable safety profile. The study was headed by Barbara Jason, Ph.D., and the findings, published in<http://archinte.jamanetwork.com/article.aspx?articleid=1764009>*[JAMA Internal Medicine](http://archinte.jamanetwork.com/article.aspx?articleid=1764009)*, are based on data from a 12-week randomized, double-blind, placebo-controlled study of 150 subjects with alcohol dependence.

"This is an impressive and revealing study," Marc Galanter, M.D., a professor of psychiatry and director of the Division of Alcoholism and Drug Abuse at New York University, told *Psychiatric News. *"The authors, however, point out that approved medications are prescribed for only 9% of American alcoholics. Why is this? One reason is that for addiction, a chronic disease, clinicians are most likely to use medications with a demonstrated long-term impact, like buprenorphine for opioid dependence. The impact of gabapentin on alcoholism (like that of naltrexone) is a meaningful, but still limited step toward this goal."

On the other hand, as the researchers point out in their report, "Unlike other approved treatments for alcohol dependence that are prescribed by a small number of specialists, gabapentin may be more readily utilized by primary care physicians."

Information about how the outcome of alcoholism treatment may be determined by a person's genetics can be found in the *Psychiatric News *article ["Genes May Determine Drugs' Alcohol-Treatment Success."](http://psychnews.psychiatryonline.org/newsarticle.aspx?articleid=1744449) Extensive information about alcohol dependence and medications to treat it can be found in the new American Psychiatric Publishing book, [*Clinical Manual of Addiction Psychopharmacology, Second Edition.*](http://www.appi.org/SearchCenter/Pages/SearchDetail.aspx?ItemId=62440) Also see the report  
["Gabapentin Combined With Naltrexone forthe Treatment of Alcohol Dependence"](http://ajp.psychiatryonline.org/article.aspx?articleid=115980) in the *American Journal of Psychiatry*.

(Image: Alexey Lysenko/Shutterstock.com)

[alcohol dependence](https://alert.psychnews.org/tag/alcohol-dependence), [medications for alcohol dependence](https://alert.psychnews.org/tag/medications-for-alcohol-dependence), [gabapentin](https://alert.psychnews.org/tag/gabapentin)

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