Monday, October 31, 2016

Higher Heart Rate in Late Adolescence May Predict Future Psychiatric Disorders

A study of more than one million Swedish military draftees published last week in JAMA Psychiatry suggests heightened heart rate and blood pressure at age 18 may be associated with higher levels of psychiatric disorders later in life.

The highest risk from an elevated resting heart rate in late adolescence was found for obsessive-compulsive disorder (OCD); men with resting heart rates above 82 beats per minute had a 69 percent increased risk for OCD compared with those with heart rates below 62 beats per minute, wrote Antti Latvala, Ph.D., of the Karolinska Institutet and the Department of Public Health at the University of Helsinki and colleagues.

Linking several Swedish national registers with longitudinal data available through the end of 2013, Latvala and colleagues compared psychiatric disorder diagnoses in men drafted from 1969 to 2010. (Men with registered diagnoses before drafting were excluded from the study.)

In addition to being at a higher risk of developing OCD later in life, men with resting heart rates above 82 beats per minute had a 21 percent higher risk for schizophrenia and an 18 percent higher risk for anxiety. Analysis of blood pressure measurements from the group revealed an association between higher diastolic blood pressure and increased risk of anxiety, OCD, and schizophrenia. The study also found that a lower resting heart rate was associated with substance use disorders and convictions for violent crimes.

“Increased heart rate is seen in many psychiatric disorders, but showing that increased heart rate predicts obsessive-compulsive disorder, anxiety disorders, and schizophrenia is very original,” Ranga Krishnan, M.B., Ch.B., dean of Rush Medical College in Chicago, and who was not involved in the study, told Psychiatric News.

“[The study] raises the possibility that autonomic changes can predict later development of these disorders and raises intriguing questions about how this could happen,” said Krishnan. “More research is needed.”

For related information, see the Psychiatric News article “Depression Increases Stroke Risk, Even After Symptoms Remit.”

(Image: iStock/Sebastian Kaulitzki)


The content of Psychiatric News does not necessarily reflect the views of APA or the editors. Unless so stated, neither Psychiatric News nor APA guarantees, warrants, or endorses information or advertising in this newspaper. Clinical opinions are not peer reviewed and thus should be independently verified.